Zevtaxel 60mg - Cabazitaxel Injection

Zevtaxel 60mg Injection contains the active constituent cabazitaxel. It is an anticancer medicine used with steroid medicine prednisone or prednisolone to treat people with hormone-refractory metastatic prostate cancer that has progressed after treatment with other anticancer medications, including docetaxel. Cancer is an abnormal and uncontrolled multiplication of cells. Many early-stage prostate cancers need normal testosterone (male hormone) levels to grow. In hormone-refractory metastatic prostate cancer, cancer keeps growing even when the amount of testosterone in the body is reduced to low levels. This medicine should not be used if you have a severe abnormal liver function or have recently been vaccinated against yellow fever. 

Its major toxicities include myelosuppression, neurotoxicity, and allergic reactions. Neutropenia is the most common adverse reaction to this drug. Monitoring of complete blood counts is essential on a weekly basis during cycle 1 and before each treatment cycle thereafter so that the dose can be adjusted, if needed. Vaccination with a live attenuated vaccine should be avoided in patients receiving the medicine, instead killed or inactivated vaccines can be administered.

Consult your doctor before using this medication if you are pregnant or plan to have a baby. This drug is unsafe to use during pregnancy as it causes harm to an unborn fetus. Your healthcare practitioner will conduct a pregnancy test before you start treatment with this drug. Discuss with your doctor effective birth control methods and utilize them for at least two weeks following the last dose. Avoid breastfeeding your baby while on the treatment as it is unknown if this drug passes into the breast milk.